The route begins in the west and rather than simply intersecting Shira Plateau (like Machame), Lemosho crosses it from Shira Ridge to Shira Camp. Climbers encounter low traffic until the route joins the Machame route. Afterwards, Lemosho follows the same route through Lava Tower, Barranco and Barafu, known as the southern circuit. The Lemosho route is one of the newer routes on Mount Kilimanjaro.
The minimum number of days required for this route is six days, although eight days is ideal.